Why the study?
Does vasodilatation or blood pressure reduction drive the correction of small artery structure during antihypertensive treatment in patients with essential hypertension?
Population
49 patients with essential hypertension, comprising 21 never-treated patients and 28 beta-blocker-treated…
Comparison
Antihypertensive treatment for 6 months. vs Baseline measurements.
Design
Cohort
Follow-up
6 months
Authors
Loading...
May support prioritizing vasodilatation over BP reduction for resistance artery remodeling in hypertension; leaves open confirmation in randomized trials.
Does vasodilatation or blood pressure reduction drive the correction of small artery structure during antihypertensive treatment in patients with essential hypertension?
Correction of resistance artery structure in essential hypertension appears to depend on the degree of vasodilatation achieved rather than the extent of blood pressure reduction.
Mathiassen et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: