Population
Isolated canine left caudal lobe
Design
Preclinical
Authors
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Questions alveolar pressure as backpressure in pulmonary flow; challenges West model but leaves open human translation.
This preclinical study refines the West model of pulmonary circulation by demonstrating that critical pressure or pulmonary venous pressure, rather than alveolar pressure, acts as the pertinent backpressure to flow in zone 3.
SooHoo et al. (1987) studied this question.
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