Why the study?
How do different antihypertensive drugs affect platelet function and fibrinolytic activity in healthy volunteers and patients with essential hypertension?
Population
Healthy volunteers and patients with mild-to-moderate essential hypertension
Comparison
Antihypertensive drugs including calcium… vs Normotensive controls, placebo, or active…
Design
Review
Authors
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Supports considering hemostatic effects in antihypertensive selection; leaves open translation to CV outcomes.
How do different antihypertensive drugs affect platelet function and fibrinolytic activity in healthy volunteers and patients with essential hypertension?
Different antihypertensive drugs have varying effects on platelet function and fibrinolytic activity, which may influence their impact on cardiovascular morbidity and mortality.
Winther et al. (1991) studied this question.
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