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February 3, 2010Current Opinion in Cardiology

Ultrafiltration in the management of acute decompensated heart failure

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Why the study?

Does ultrafiltration improve fluid removal compared to standard intravenous diuretics in patients with acute decompensated heart failure?

Population

Patients with acute decompensated heart failure and volume overload

Comparison

Ultrafiltration vs Standard treatment with intravenous diuretics

Design

Review

Authors

LMLisa MielniczukHeart Failure & TransplantHHHaissam HaddadHoly Spirit University of KaslikRDRoss A. DaviesThe University of Texas Southwestern Medical Center

Discussion

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Overview

May support ultrafiltration for refractory volume overload in decompensated HF; leaves open nephroprotective effects pending randomized trials.

Structured PICO

Does ultrafiltration improve fluid removal compared to standard intravenous diuretics in patients with acute decompensated heart failure?

P
Population
Patients with acute decompensated heart failure and volume overload
I
Intervention
Ultrafiltration
C
Comparator
Standard treatment with intravenous diuretics

Ultrafiltration is a feasible and potentially more effective alternative to standard intravenous diuretics for managing volume overload in acute decompensated heart failure, though further research is needed on long-term impacts.

Cite This Study

Mielniczuk et al. (2010) studied this question.

synapsesocial.com/papers/6a726fc0f44fa9f079dfeb8ahttps://doi.org/10.1097/hco.0b013e3283358a2b

Topics

HFrEF treatmentHeart failure hospitalizationHeart failure
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Haemodynamic and Hormone Responses to Acute and Chronic Frusemide Therapy in Congestive Heart Failure1980 · 174 citations
  2. 2The severe cardiorenal syndrome: ‘Guyton revisited’2004 · 462 citations
  3. 3Executive summary of the guidelines on the diagnosis and treatment of acute heart failure2005 · 1,183 citations
  4. 4Sustained cardiac diastolic changes elicited by ultrafiltration in patients with moderate congestive heart failure: pathophysiological correlates.1993 · 82 citations