What question did this study set out to answer?

To determine how temperature alters muscle energy liberation, isometric twitch force, and activation heat across different muscle lengths.

June 1, 1979The Journal of PhysiologyOpen Access

Effects of temperature on tension, tension‐dependent heat, and activation heat in twitches of frog skeletal muscle.

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Population

Frog skeletal muscle

Comparison

Temperature elevation from 0 to 20 degrees C vs Baseline temperature (0 degrees C)

Design

Preclinical

Authors

JRJack A. RallThe Ohio State University

Discussion

Member takes

Implication

Findings in frog muscle warrant caution before extrapolating to cardiac tissue; leaves open temperature dependence of myocardial energetics in humans.

Key Points

To determine how temperature alters muscle energy liberation, isometric twitch force, and activation heat across different muscle lengths.
Measured isometric twitch force and energy liberation (heat plus work) across temperatures from 0 to 20 °C.
Tested isolated frog skeletal muscle preparations at resting length and extended length (approximately 1.35 times resting length).
Elevating temperature from 0 to 20 °C progressively decreased twitch force and energy liberation at resting length, with force diminishing to a greater extent than energy.
Energy liberation at extended muscle length (activation heat) remained independent of temperature, indicating that calcium release and cycling per stimulus are unaffected by thermal shifts or muscle length.

Structured PICO

Population

Frog skeletal muscle

Intervention

Temperature elevation from 0 to 20 degrees C

Comparator

Baseline temperature (0 degrees C)

Outcome

Muscle energy liberation (heat plus work production) and isometric twitch force productionsurrogate

In frog skeletal muscle, elevating temperature from 0 to 20 degrees C decreases force production and energy liberation, but activation heat remains independent of temperature.

Cite This Study

Jack A. Rall (1979) studied this question.

synapsesocial.com/papers/6a72753584cc45bb7be01fa7 https://doi.org/10.1113/jphysiol.1979.sp012811

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Implication

Findings in frog muscle warrant caution before extrapolating to cardiac tissue; leaves open temperature dependence of myocardial energetics in humans.

Effects of temperature on tension, tension‐dependent heat, and activation heat in twitches of frog skeletal muscle.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Effects of temperature on tension, tension‐dependent heat, and activation heat in twitches of frog skeletal muscle.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider