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June 1, 2000Coronary Artery Disease

Mortality, mode of death and risk indicators for death during 5 years after coronary artery bypass grafting among patients with and without a history of diabetes mellitus

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Why the study?

Does a history of diabetes mellitus increase mortality and affect the mode of death in patients undergoing coronary artery bypass grafting?

Population

1,998 patients in western Sweden who underwent coronary artery bypass grafting without concomitant valve…

Comparison

History of diabetes mellitus vs No history of diabetes mellitus

Design

Cohort

Follow-up

5 years

Authors

JHJohan HerlitzGeneral CardiologyGWGunnar Brandrup WognsenAstraZeneca (Sweden)BKBjörn W. KarlsonAstraZeneca (Sweden)

Discussion

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Implication

Diabetes associated with higher post-CABG mortality; supports risk stratification yet leaves open need for randomized intervention trials.

Structured PICO

Does a history of diabetes mellitus increase mortality and affect the mode of death in patients undergoing coronary artery bypass grafting?

P
Population
1,998 patients in western Sweden who underwent coronary artery bypass grafting (CABG) without concomitant valve surgery and who had no previous CABG between June 1988 and June 1991. 242 (12%) had a history of diabetes.
I
Intervention
History of diabetes mellitus
C
Comparator
No history of diabetes mellitus
O
Outcome
Mortality at 5 yearshard clinical

Patients with diabetes have twice the 5-year mortality risk compared to non-diabetic patients following CABG, with higher rates of cardiac death and in-hospital mortality.

Cite This Study

Herlitz et al. (2000) studied this question.

synapsesocial.com/papers/6a727e0ff44fa9f079dff534https://doi.org/10.1097/00019501-200006000-00007
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of Diabetes Mellitus on the Results of Coronary Bypass Surgery1986 · 103 citations
  2. 2Mortality, Place and Mode of Death and Reinfarction during a Period of 5 Years after Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients2008 · 38 citations
  3. 3The evolution of medical and surgical therapy for coronary artery disease. A 15-year perspective1989 · 314 citations
  4. 4Myocardial infarction in patients with diabetes mellitus1988 · 239 citations
  5. 5Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction.1987 · 2,379 citations