Key result
A history of hypertension in patients undergoing first-time CABG was associated with a higher 5-year mortality compared to those without hypertension (RR 1.4; 95% CI 1.1-1.8).
Why the study?
Does a history of hypertension increase the risk of death and angina symptoms in the 5 years following coronary artery bypass grafting?
Cohort (n=1,997)
Does a history of hypertension increase the risk of death and angina symptoms in the 5 years following coronary artery bypass grafting?
Relative Risk: 1.4 (95% CI 1.1–1.8)
A history of hypertension is a significant risk factor for increased 5-year mortality and non-cardiac death following coronary artery bypass grafting.
AIM: To describe mortality, risk indicators for death, place and mode of death, and symptoms of angina pectoris among survivors in the 5 years after coronary artery bypass grafting (CABG) in patients with and without a history of hypertension. METHODS: All patients in western Sweden who underwent CABG without concomitant valve surgery and without previously performed CABG between June 1988 and June 1991. RESULTS: A total of 1997 patients were included in the analysis, 740 (37%) of whom had a history of hypertension. Patients with no history had a 5-year mortality of 12.4%. The corresponding relative risk for hypertensives was 1.4 (95% CI 1.1-1.8). Risk factors for death appeared similar in patients with and without a history of hypertension. Patients with hypertension had an increased risk of death in hospital and an increased risk of a non-cardiac death. Among survivors after 5 years, patients with a history of hypertension tended to have a higher prevalence of symptoms equivalent to angina pectoris. CONCLUSIONS: Patients with a history of hypertension have an increased risk of death in the 5 years after CABG. Risk factors for death appear similar in patients with and without a history of hypertension. Patients with hypertension have a particularly increased risk of death in hospital and of death judged as non-cardiac.
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Johan Herlitz (1999) conducted a cohort in Coronary Artery Disease post-CABG (n=1,997). History of hypertension vs. No history of hypertension was evaluated on 5-year mortality (RR 1.4, 95% CI 1.1-1.8). A history of hypertension in patients undergoing first-time CABG was associated with a higher 5-year mortality compared to those without hypertension (RR 1.4; 95% CI 1.1-1.8).
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