Why the study?
Does the ACE genetic polymorphism DD genotype worsen echocardiographic outcomes in patients with non-ischemic heart failure compared to DI or II genotypes?
Does the ACE genetic polymorphism DD genotype worsen echocardiographic outcomes in patients with non-ischemic heart failure compared to DI or II genotypes?
In Brazilian patients with non-ischemic heart failure, the ACE DD genotype is independently associated with worse echocardiographic remodeling compared to the DI genotype.
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ACE DD genotype associated with worse LV remodeling in non-ischemic HF; hypothesis-generating, should not yet change practice.
Albuquerque et al. (2013) studied this question.
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