Why the study?
Does oral quinine suppress ventricular arrhythmias in patients with frequent spontaneous ventricular ectopy or inducible ventricular tachycardia?
Does oral quinine suppress ventricular arrhythmias in patients with frequent spontaneous ventricular ectopy or inducible ventricular tachycardia?
Quinine demonstrates antiarrhythmic efficacy in humans by suppressing spontaneous ventricular ectopy and prolonging the ventricular effective refractory period without prolonging the QTc interval.
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Hypothesis-generating for quinine in ventricular arrhythmia suppression; randomized trials needed before any clinical role.
Sheldon et al. (1995) studied this question.
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