Correlation of E/E’ on echocardiography and BNP levels in diastolic dysfunction patients visiting Mardan Medical Complex

Introduction: Assessment of diastolic heart function can be challenging due to various factors. Doppler echocardiography is useful but has limitations, pointing to the need for more accurate tests. Tissue Doppler imaging (TDI) is a promising ultrasound technique for diastolic prediction. The E/E' ratio is commonly used to determine LV filling pressures. B-natriuretic peptide (BNP) levels may also indicate diastolic dysfunction. Aims: To compare the BNP levels with E/E' ratios in this investigation to evaluate their effectiveness in predicting LV pressures. Methodology: This study compared BNP levels with E/E' in patients with diastolic dysfunction. Patients with reduced LV function were excluded, and all participants gave informed consent. The study found that BNP levels were a useful diagnostic tool and could be compared with E/E' using ROC curves. Results: The study included 100 patients with diastolic dysfunction and excluded those with reduced LV function. The patients had a mean age of 60.51, with 60% males and 40% females. The majority of patients were in NYHA class II (56%), followed by NYHA class III (28%) and NYHA class IV (16%). The study also provided mean BNP levels for patients with different E/E' ratios.