Population
Cynomolgus monkey model of lipopolysaccharide (LPS)-induced thrombocytopenia
Design
Preclinical
Follow-up
24 hours
Authors
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sGPVI may track acute platelet activation dynamically; hypothesis-generating for clinical biomarker validation in humans.
Plasma sGPVI closely reflects platelet activation in the bloodstream with a short half-life, suggesting utility as a biomarker for platelet activation and monitoring anti-platelet therapy.
Naitoh et al. (2014) studied this question.
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