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December 1, 1989American Journal of Hypertension

Myocardial Collagen Remodeling in Pressure Overload Hypertrophy

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KWKarl T. WeberJJJorge JalilJJJoseph S. Janicki

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Overview

Supports antifibrotic investigation in pressure-overload hypertrophy; leaves open clinical efficacy pending prospective trials.

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Cite This Study

Weber et al. (1989) studied this question.

synapsesocial.com/papers/6a72b663febe604dd70abc23https://doi.org/10.1093/ajh/2.12.931
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle.1989 · 496 citations
  2. 2Pathologic Hypertrophy with Fibrosis: The Structural Basis for Myocardial Failure1992 · 90 citations
  3. 3Regulatory Mechanisms of Myocardial Hypertrophy and Fibrosis: Results of in vivo Studies2008 · 40 citations
  4. 4Myocardial fibrosis in hypertensive heart disease: an overview of potential regulatory machanisms1995 · 74 citations
  5. 5Collagen cross-linking: new dimension to cardiac remodeling2003 · 35 citations