Why the study?
Does TCV-116 or delapril attenuate left ventricular dilatation and haemodynamic alterations after myocardial infarction in hypertensive and normotensive rats?
Does TCV-116 or delapril attenuate left ventricular dilatation and haemodynamic alterations after myocardial infarction in hypertensive and normotensive rats?
Angiotensin II type 1 receptor antagonists and ACE inhibitors attenuate left ventricular dilatation and adverse hemodynamic alterations following myocardial infarction in both hypertensive and normotensive rat models.
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Supports preclinical post-MI remodeling studies in hypertension; leaves open translation to human therapy.
Nishikimi et al. (1995) studied this question.
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