Why the study?
Does delapril improve survival and reduce infarct expansion in spontaneously hypertensive rats following myocardial infarction?
Does delapril improve survival and reduce infarct expansion in spontaneously hypertensive rats following myocardial infarction?
In a rat model of myocardial infarction, ACE inhibition with delapril improved survival in hypertensive rats with left ventricular hypertrophy, although it did not further reduce infarct expansion compared to the effects of hypertrophy alone.
Authors
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May improve post-MI survival in hypertensive rats with LVH; hypothesis-generating for ACE inhibition in patients pending human trials.
Masato Morita (1996) studied this question.
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