Why the study?
Does trandolapril and/or verapamil prevent microalbuminuria in subjects with type 2 diabetes, hypertension, and normoalbuminuria?
Does trandolapril and/or verapamil prevent microalbuminuria in subjects with type 2 diabetes, hypertension, and normoalbuminuria?
In patients with type 2 diabetes, hypertension, and normoalbuminuria, trandolapril (with or without verapamil) prevents microalbuminuria, whereas verapamil alone does not.
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May support trandolapril to prevent microalbuminuria in diabetic hypertension; leaves open additive value of verapamil.
In subjects with type 2 diabetes and hypertension but with normoalbuminuria, the use of trandolapril plus verapamil and trandolapril alone decreased the incidence of microalbuminuria to a similar extent.The effect of verapamil alone was similar to that of placebo.
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Zandi‐Nejad et al. (2005) studied this question.
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