Why the study?
Does human insulin improve recovery time from diabetic ketoacidosis compared to porcine insulin?
Population
21 patients with diabetic ketoacidosis (DKA)
Comparison
Semisynthetic human insulin 8 U/h i.v., with… vs Monocomponent porcine insulin 8 U/h i.v., with…
Design
RCT, randomized, double-blind
Authors
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No clinically meaningful DKA recovery difference; confirms human and porcine insulin are interchangeable.
Does human insulin improve recovery time from diabetic ketoacidosis compared to porcine insulin?
Human insulin may lead to slightly faster recovery of some metabolic parameters in DKA compared to porcine insulin, but the difference does not appear clinically important.
Storms et al. (1987) studied this question.
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