Prognostic factors of patients with myocardial infarction with nonobstructive coronary artery disease: a seven-year longitudinal follow-up
Why the study?
MINOCA is common and associated with major adverse events, but unlike obstructive coronary artery disease, data regarding its prognosis are scarce.
Population
1,544 consecutive MINOCA patients at a large tertiary medical center in Israel
Design
Retrospective cohort study
Follow-up
Median 7 years
Authors
Discussion
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Member takes
Implication
Identifies risk factors for MAE in MINOCA; leaves open whether targeted strategies improve prognosis.
Structured PICO
P
Population
1,544 patients with myocardial infarction with nonobstructive coronary arteries (MINOCA), mean age 61±13, 46% female, from a single center in Israel. Excluded: probable alternative causes for myocardial injury such as stress-induced cardiomyopathy and myocarditis.
O
Outcome
Major adverse events (MAE), defined as all-cause mortality or recurrent MIcomposite
In patients with MINOCA, older age, LVEF <40%, and increased serum-creatinine are associated with increased risk of long-term major adverse events, while female gender, higher hemoglobin, and sinus rhythm are associated with lower risk.
Cite This Study
Tsaban et al. (2022) studied this question.