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October 1, 2021European Heart JournalOpen Access

Long-term outcome of patients with myocardial infraction with nonobstructive coronary arteries

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Why the study?

MINOCA is a condition of growing interest, but data were needed to evaluate long-term prognosis and identify risk factors associated with long-term mortality.

Population

1544 patients aged ≥18 years hospitalized with AMI and non-obstructive coronary lesions (<50% stenosis)

Design

Retrospective observational cohort study

Follow-up

Mean follow-up time of 8.5 years

Authors

OBOrit BarrettCedars-Sinai Medical CenterONO Edry NadivBen-Gurion University of the NegevIPIdo PelesBen-Gurion University of the Negev

Discussion

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Implication

MINOCA patients show notable long-term mortality with identifiable risk factors; leaves open optimal management strategies pending prospective trials.

Structured PICO

P
Population
1,544 patients aged ≥18 years hospitalized with a primary diagnosis of acute myocardial infarction (AMI) and non-obstructive lesions (<50% stenosis in all coronary arteries), mean age 61, 46% female.
O
Outcome
Long-term mortalityhard clinical

MINOCA is associated with a favorable short-term prognosis but significant long-term mortality, particularly in older patients and those with concomitant congestive heart failure.

Cite This Study

Barrett et al. (2021) studied this question.

synapsesocial.com/papers/6a72c932e36a167817e412dchttps://doi.org/10.1093/eurheartj/ehab724.1351
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries2019 · 158 citations
  2. 2Clinical characteristics and prognosis of myocardial infarction with non-obstructive coronary arteries: A prospective single-center study2020 · 30 citations
  3. 3Prognostic factors of patients with myocardial infarction with nonobstructive coronary artery disease: a seven-year longitudinal follow-up2022 · 1 citations
  4. 4Myocardial infarction with nonobstructive coronary arteries2018 · 37 citations
  5. 5MINOCA, experience of a single tertiary center with a high volume of ACS2024