Why the study?
What are the circulatory and respiratory effects of different doses of intravenous Prostaglandin E1 in healthy male subjects?
Population
8 healthy male subjects
Design
Other
Authors
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Healthy volunteer data warrant caution before clinical use; leaves open applicability in patients.
What are the circulatory and respiratory effects of different doses of intravenous Prostaglandin E1 in healthy male subjects?
Intravenous Prostaglandin E1 induces dose-dependent hyperkinetic circulatory changes and respiratory effects, including alveolar hyperventilation at higher doses, in healthy men.
Carlson et al. (1969) studied this question.
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