Why the study?
What are the clinical and metabolic effects of escalating doses of intravenous Prostaglandin E1 in healthy men?
Population
8 healthy male subjects
Design
Case_series
Follow-up
15-30 min after the end of the infusion
Authors
Loading...
Severe side effects may limit higher-dose intravenous PGE1; leaves open metabolic effects in clinical populations.
What are the clinical and metabolic effects of escalating doses of intravenous Prostaglandin E1 in healthy men?
Intravenous Prostaglandin E1 in healthy men causes significant adverse clinical symptoms like severe headache and abdominal cramps, alongside increased mobilization of free fatty acids and glycerol.
Carlson et al. (1968) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: