Population
Murine TIMP gene model (plasmids transfected into cells)
Design
Preclinical
Authors
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Hypothesis-generating for TIMP regulation in viral cardiac contexts; warrants human validation before any clinical consideration.
Intron 1 of the murine TIMP gene contains transcription regulatory elements that modulate gene expression and confer virus inducibility.
Coulombe et al. (1988) studied this question.
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