Why the study?
Can quetiapine induce fatal neuroleptic malignant syndrome in an elderly patient with Parkinson disease?
Population
1 elderly female patient with Parkinson disease who developed acute psychosis
Design
Case_report
Follow-up
short (died shortly after admission)
Authors
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Quetiapine may trigger fatal NMS in Parkinson disease; leaves open safer antipsychotic options for this population.
Can quetiapine induce fatal neuroleptic malignant syndrome in an elderly patient with Parkinson disease?
Quetiapine can rarely cause severe, abrupt-onset, and fatal neuroleptic malignant syndrome, necessitating prompt recognition and drug withdrawal.
Schattner et al. (2015) studied this question.