Why the study?
Does quetiapine cause neuroleptic malignant syndrome with extrapyramidal symptoms?
Population
34-year-old male with a history of severe brain damage, mental retardation, and seizures
Design
Case_report
Follow-up
7 days
Key result
A 34-year-old male developed neuroleptic malignant syndrome with extrapyramidal symptoms after receiving quetiapine 200 mg three times daily for at least a month without recent dosage adjustments.
Authors
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Quetiapine may trigger NMS with EPS at stable doses; single case leaves open causality and generalizability.
Case Report (n=1)
Does quetiapine cause neuroleptic malignant syndrome with extrapyramidal symptoms?
Clinicians should be aware that neuroleptic malignant syndrome with extrapyramidal symptoms can occur with quetiapine at steady state doses without recent dosage adjustments.
Gortney et al. (2009) conducted a case report in Neuroleptic malignant syndrome (n=1). Quetiapine was evaluated on Development of neuroleptic malignant syndrome with extrapyramidal symptoms. A 34-year-old male developed neuroleptic malignant syndrome with extrapyramidal symptoms after receiving quetiapine 200 mg three times daily for at least a month without recent dosage adjustments.