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July 18, 2012Journal of Bone and Joint Surgery

The Dangers of Stopping a Trial Too Early

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Authors

MBMatthias BrielUniversity Hospital of BaselDBDirk BasslerUniversity of ZurichAWAmy T. WangTownsville Hospital

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Implication

Early stopping of RCTs for benefit warrants clinical caution in adoption; leaves open optimal stopping rules for future trials.

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Cite This Study

Briel et al. (2012) studied this question.

synapsesocial.com/papers/6a72e734da24de05641ae767https://doi.org/10.2106/jbjs.k.01412
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