Prognostic value of SYNTAX scores for Predicting Major Cardiac Adverse events in Patients with acute Myocardial Infarction who Underwent Primary Percutaneous Coronary Intervention

Background: SYNTAX (SS) and clinical SYNTAX (CSS) scores are widely used in clinical practice to predict major adverse cardiac events (MACE) after elective and primary percutaneous intervention (PCI). We sought to investigate prognostic values for SS and CSS with more accurate predictive ability for MACE. Methods: All patients of two referral hospitals who were diagnosed with ACS were recruited for the study. SS and CSS were calculated by researchers blinded to the operators using the designed web-based software and clinical factors. SS was classified into three categories: low SS1:0 – 11.75, moderate SS2:11.75 – 23.25, and high SS3: ≥ 23.25. CSS was classified as follows: low CSS1:0-22.95, moderate CSS2:22.95-35.95, and high CSS3: ≥ 35.95. All patients were advised to visit our clinic at 1, 6, and 12 months. Clinical examination results and MACE were recorded in the hospital clinical system database. Results: We recorded the clinical data of 296 patients. After 12 months of follow-up, MACE occurred in 16.8% of SS3, 9.3% of SS2, and 8.2% of SS1 cases. MACE accounted for 14.0% of CSS3, 11.3% of CSS2, and 8.1% of CSS1 cases. Conclusions: The classification of SS (low SS1:0 – 11.75, moderate SS2:11.75 – 23.25, high SS3: ≥ 23.25) and CCS (low CSS1:0-22.95, moderate CSS2:22.95-35.95, high CSS3: ≥ 35.95) had important roles in the risk assessment of patients with ACS who underwent primary PCI.