Key result
High SYNTAX score predicts ~99% higher 2-year MACE risk after primary PCI for STEMI.
Why the study?
The prognostic value of interventional complexity assessed by SYNTAX score in STEMI patients undergoing primary PCI was unclear.
Does the initial SYNTAX score predict major adverse cardiac events in patients undergoing primary percutaneous coronary intervention for STEMI?
Comparison
High (≥33) and intermediate (23-32) SYNTAX scores vs low (≤22) SYNTAX score
Design
Cohort study
Follow-up
2 years
Authors
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SS stratification may identify higher-risk STEMI patients post-PPCI; leaves open whether it should guide staged revascularization.
Cohort (n=674)
Does the initial SYNTAX score predict major adverse cardiac events in patients undergoing primary percutaneous coronary intervention for STEMI?
Hazard Ratio: 1.99 (95% CI 1.16–3.41)
p-value: p=0.01
The initial SYNTAX score provides significant prognostic information for predicting long-term major adverse cardiac events in patients undergoing primary PCI for STEMI.
Brown et al. (2013) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=674). High SYNTAX score (≥33) vs. Low SYNTAX score (≤22) was evaluated on Major adverse cardiac events (MACE) (HR 1.99, 95% CI 1.16-3.41, p=0.01). A high SYNTAX score (≥33) independently predicted major adverse cardiac events at 2 years in patients undergoing primary PCI for STEMI compared to a low score (HR 1.99; 95% CI 1.16-3.41; P=0.01).
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