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December 1, 2021BMC Cardiovascular DisordersOpen Access

Prognostic value of the SYNTAX score on myocardial injury and salvage in STEMI patients after primary percutaneous coronary intervention: a single-center retrospective observational study

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Why the study?

Evidence about the association of the SYNTAX score with myocardial salvage in STEMI patients was still needed.

Does a higher SYNTAX score predict greater myocardial injury and lower myocardial salvage in STEMI patients after primary PCI?

Population

149 STEMI patients undergoing primary PCI within 12 h from symptom onset

Comparison

Low SS (SS ≤ 22) vs mediate-high SS (SS > 22)

Design

Single-center retrospective observational study

Authors

GGGuangren GaoCangzhou Central HospitalLFLianrong FengCangzhou Central HospitalJFJinguo FuCangzhou Central Hospital

Discussion

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Overview

Higher SYNTAX score was associated with larger infarcts and less salvage post-primary PCI in STEMI; leaves open incremental value for risk stratification.

Structured PICO

Does a higher SYNTAX score predict greater myocardial injury and lower myocardial salvage in STEMI patients after primary PCI?

P
Population
149 STEMI patients who had undergone primary PCI within 12 h from symptom onset
I
Intervention
Mediate-high SYNTAX score (SS > 22)
C
Comparator
Low SYNTAX score (SS ≤ 22)
O
Outcome
Myocardial injury (infarct size) and myocardial salvage index assessed by cardiac magnetic resonance (CMR) during hospitalizationsurrogate

In STEMI patients undergoing primary PCI, a higher SYNTAX score is independently associated with larger infarct size and reduced myocardial salvage on CMR.

Cite This Study

Gao et al. (2021) studied this question.

synapsesocial.com/papers/6a8a89a8439f8b7e01435548https://doi.org/10.1186/s12872-021-02395-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Infarct size following complete revascularization in patients presenting with STEMI: a comparison of immediate and staged in-hospital non-infarct related artery PCI subgroups in the CvLPRIT study2016 · 16 citations
  2. 2Fourth Universal Definition of Myocardial Infarction (2018)2018 · 3,872 citations
  3. 3Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging2015 · 8,528 citations
  4. 4Using the SYNTAX score to predict myocardial injury early after on-pump coronary artery bypass surgery: 76 a single-centre experience analysis2020 · 4 citations
  5. 5Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction2011 · 100 citations