September 2, 2019Catheterization and Cardiovascular Interventions
Prediction of long‐term patient outcome after contemporary left main stenting using the SYNTAX and SYNTAX II scores: A comparative analysis from the FAIL‐II multicenter registry (failure in left main study with 2nd generation stents‐Cardiogroup III study)
Why the study?
The predictive value of the SYNTAX Score-II for long-term mortality in patients treated with left main PCI using second-generation drug-eluting stents remained to be established.
Does the SYNTAX Score-II (SS-II) improve prediction of long-term mortality compared to the original SYNTAX score (SS) in patients undergoing left main PCI with second-generation DES?
Population
804 patients undergoing left main PCI with second-generation DES in the FAILS-2 registry
Comparison
SS-II risk tertiles vs original SS
Design
Multicenter registry study
Follow-up
5.2 ± 3.6 years
Authors
Discussion
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Member takes
Implication
SS-II may enhance mortality risk stratification after LM-PCI; leaves open whether it improves decisions over SS in prospective use.
Structured PICO
Does the SYNTAX Score-II (SS-II) improve prediction of long-term mortality compared to the original SYNTAX score (SS) in patients undergoing left main PCI with second-generation DES?
P
Population
804 patients treated with left main percutaneous coronary intervention (LM-PCI) using second-generation drug-eluting stents (DES) from the FAILS-2 multicenter registry.
I
Intervention
Risk stratification using the SYNTAX Score-II (SS-II)
C
Comparator
Risk stratification using the original SYNTAX score (SS)
O
Outcome
All-cause mortality at long-term follow-up (5.2 ± 3.6 years)hard clinical
The SYNTAX Score-II is superior to the original SYNTAX score for predicting long-term mortality after left main PCI with second-generation DES, though acute coronary syndrome and diabetes remain independent risk factors not captured by the score.
Cite This Study
Cerrato et al. (2019) studied this question.