Key result
The SYNTAX score II was an independent predictor of 2-year mortality (HR 1.66; 95% CI 1.03-2.68; P=0.04) and demonstrated superior predictive ability compared to the baseline SYNTAX score.
Why the study?
Does the SYNTAX score II improve prediction of 2-year mortality compared to baseline SYNTAX score in patients with complex CAD undergoing PCI?
Population
4,398 consecutive patients with complex coronary artery disease undergoing three-vessel and/or unprotected…
Comparison
SYNTAX score II (SS-II) risk stratification vs Baseline SYNTAX score (SS)
Design
Cohort
Follow-up
2 years
Authors
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May aid 2-year mortality stratification in complex CAD PCI; hypothesis-generating for prospective validation.
Cohort (n=4,398)
No
Does the SYNTAX score II improve prediction of 2-year mortality compared to baseline SYNTAX score in patients with complex CAD undergoing PCI?
Hazard Ratio: 1.66 (95% CI 1.03–2.68)
Absolute Event Rate: 2.7% vs 0.5%
p-value: p=0.04
The SYNTAX score II, which combines anatomical and clinical variables, is superior to the purely angiographic baseline SYNTAX score for predicting 2-year mortality in patients with complex CAD undergoing PCI.
Song et al. (2017) conducted a cohort in Complex coronary artery disease (n=4,398). SYNTAX score II (SS-II) vs. Baseline SYNTAX score was evaluated on 2-year mortality (HR 1.66, 95% CI 1.03-2.68, p=0.04). The SYNTAX score II was an independent predictor of 2-year mortality (HR 1.66; 95% CI 1.03-2.68; P=0.04) and demonstrated superior predictive ability compared to the baseline SYNTAX score.
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