Key result
A high SYNTAX Score II (>17) was associated with a significantly higher risk of all-cause mortality following percutaneous coronary intervention compared to a low score (RR 2.65; 95% CI 1.05-6.73; P=.04).
Why the study?
Because the SYNTAX Score has limitations and should be replaced by a better angiographic tool, this study systematically investigated mortality prediction using the SYNTAX Score II following PCI.
Does a high SYNTAX Score II predict higher all-cause mortality compared to a low SYNTAX Score II in patients undergoing PCI?
Population
9443 participants undergoing PCI across electronic database studies
Comparison
High vs low SYNTAX Score II across various cutoff groups
Design
Systematic review and meta-analysis
Authors
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May aid post-PCI mortality stratification; leaves open prospective validation before routine adoption.
Meta-Analysis (n=9,443)
Does a high SYNTAX Score II predict higher all-cause mortality compared to a low SYNTAX Score II in patients undergoing PCI?
Relative Risk: 2.65 (95% CI 1.05–6.73)
p-value: p=.04
A high SYNTAX Score II is associated with a significantly increased risk of all-cause mortality following PCI, supporting its use as a prognostic tool in interventional cardiology.
Yang et al. (2019) conducted a meta-analysis in Percutaneous coronary intervention (PCI) (n=9,443). High SYNTAX Score II vs. Low SYNTAX Score II was evaluated on All-cause mortality (RR 2.65, 95% CI 1.05-6.73, p=.04). A high SYNTAX Score II (>17) was associated with a significantly higher risk of all-cause mortality following percutaneous coronary intervention compared to a low score (RR 2.65; 95% CI 1.05-6.73; P=.04).
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