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July 1, 2017MedicineOpen Access

Application of the SYNTAX score in interventional cardiology

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Why the study?

Does a high SYNTAX score predict worse adverse cardiovascular outcomes compared to a low SYNTAX score in patients undergoing percutaneous coronary intervention?

Population

16 studies (RCTs and observational) pooling 19,751 participants undergoing percutaneous coronary intervention

Comparison

High SYNTAX score vs Low SYNTAX score

Design

Meta-analysis

Authors

PBPravesh Kumar BundhunInterventional CardiologyYSYashna SookhareeABAnita Bholee

Discussion

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Implication

SYNTAX integration in PCI decisions remains uncertain; leaves open need for prospective validation before routine use.

Structured PICO

Does a high SYNTAX score predict worse adverse cardiovascular outcomes compared to a low SYNTAX score in patients undergoing percutaneous coronary intervention?

P
Population
16 studies (RCTs and observational) pooling 19,751 participants undergoing percutaneous coronary intervention
I
Intervention
High SYNTAX score
C
Comparator
Low SYNTAX score
O
Outcome
Postinterventional adverse cardiovascular outcomes (including mortality, cardiac death, myocardial infarction, major adverse cardiac events, repeated revascularization, and stent thrombosis)hard clinical

A high SYNTAX score is strongly associated with increased risks of mortality, myocardial infarction, MACE, and stent thrombosis following PCI, confirming its utility in clinical risk stratification.

Cite This Study

Bundhun et al. (2017) studied this question.

synapsesocial.com/papers/6a90df173f101abad173c7fahttps://doi.org/10.1097/md.0000000000007410

Topics

Coronary artery diseasePercutaneous coronary intervention
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Validation of the Ability of SYNTAX and Clinical SYNTAX Scores to Predict Adverse Cardiovascular Events After Stent Implantation2015 · 18 citations
  2. 2Drug-eluting stent placement versus coronary artery bypass surgery for unprotected left main coronary artery disease: A meta-analysis of randomized controlled trials2017 · 12 citations