Key result
IV steroids and aspirin restore sinus rhythm in ~100% of post-VSD closure complete heart block.
Case Report (n=2)
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Two patients with perimembranous ventricular septal defects (VSDs) and inlet extension have undergone uncomplicated transcatheter device closure using the Amplatzer membranous VSD device. Both patients developed complete heart block 2-4 days from the closure. Both patients responded well to high-dose intravenous therapy with steroids and high-dose oral anti-inflammatory aspirin. Both patients remain in normal sinus rhythm 8 weeks and 10 months, respectively, from the episode.
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Yip et al. (2005) conducted a case report in Complete heart block after transcatheter closure of perimembranous ventricular septal defect with inlet extension (n=2). High-dose intravenous steroids and high-dose oral anti-inflammatory aspirin was evaluated on Restoration and maintenance of normal sinus rhythm. High-dose IV steroids and oral aspirin restored normal sinus rhythm in 2 of 2 patients who developed complete heart block 2-4 days after transcatheter perimembranous VSD closure.
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