Why the study?
Are plasma soluble ICAM-1 levels elevated in patients with acute myocardial infarction and unstable angina compared to stable angina and controls?
Are plasma soluble ICAM-1 levels elevated in patients with acute myocardial infarction and unstable angina compared to stable angina and controls?
Plasma soluble ICAM-1 levels are elevated in acute coronary syndromes (AMI and unstable angina), suggesting an inflammatory component in the pathogenesis of ischemic myocardium.
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Elevated sICAM-1 may mark endothelial activation in ACS; hypothesis-generating and should not yet change practice.
Kaikita et al. (1997) studied this question.
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