Electrophysiologic Characteristics of Ventricular Arrhythmias Arising from the Aortic Mitral Continuity—Potential Role of the Conduction System
Key result
Ventricular arrhythmias with prepotentials were associated with a significantly higher PVC burden compared to those without prepotentials (26.1% vs. 14.9%, P=0.03).
Population
21 patients who underwent ablation of ventricular arrhythmia at the aortic mitral continuity with acute…
Comparison
Catheter ablation of ventricular arrhythmia at… vs Comparison between patients with prepotentials…
Design
Cohort
Authors
Discussion
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Implication
Prepotentials were associated with higher PVC burden; hypothesis-generating for conduction tissue targeting to improve ablation success.
Study Design
Type
Observational (n=21)
Multicenter
No
Structured PICO
P
Population
21 patients (mean age 53.2 years, 52.4% female) who underwent successful catheter ablation of ventricular arrhythmia at the aortic mitral continuity.
E
Exposure
Catheter ablation of ventricular arrhythmia at the aortic mitral continuity
C
Comparator
Comparison between patients with prepotentials (PPs) and those without PPs
O
Outcome
Electrophysiologic characteristics including presence of prepotentials, PVC burden, VEGM to QRS intervals, pace map scores, and V-H intervalssurrogate
Main Result
Absolute Event Rate: 26.1% vs 14.9%
p-value: p=0.03
Identification of prepotentials during ablation of ventricular arrhythmias at the aortic mitral continuity suggests a conduction tissue origin and may serve as a specific target to improve procedural success.
Cite This Study
Hai et al. (2014) conducted an observational in Ventricular arrhythmia at the fibrous aortic mitral continuity (n=21). Presence of prepotentials (PPs) at ablation sites vs. Absence of prepotentials was evaluated on Burden of premature ventricular complexes (PVCs) (p=0.03). Ventricular arrhythmias with prepotentials were associated with a significantly higher PVC burden compared to those without prepotentials (26.1% vs. 14.9%, P=0.03).