Population
Chylomicron and very low density lipoprotein (VLDL) substrates
Design
Preclinical
Authors
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Findings in animal models warrant clinical caution; extends kinetic model of remnant formation but requires human validation.
Lipoprotein lipase forms remnant particles from VLDL and chylomicrons through a mechanism involving decreasing catalytic rate with unchanged apparent Km.
Higgins et al. (1975) studied this question.
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