Why the study?
Does the choice of volatile anesthetic (sevoflurane, isoflurane, halothane, enflurane) affect hemodynamic responses during inhaled induction of anesthesia in healthy adults?
Population
50 ASA physical status I patients, aged 20-40 yr, scheduled for elective minor surgery.
Comparison
Inhalation of sevoflurane, isoflurane… vs Comparison between the four volatile anesthetics.
Design
Other
Follow-up
15 minutes
Authors
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Isoflurane may increase hemodynamic instability risk during induction; leaves open optimal volatile selection in vulnerable patients.
Does the choice of volatile anesthetic (sevoflurane, isoflurane, halothane, enflurane) affect hemodynamic responses during inhaled induction of anesthesia in healthy adults?
Isoflurane and enflurane induce hyperdynamic cardiovascular responses during inhaled induction, whereas sevoflurane and halothane do not, likely related to the degree of airway irritation.
Tanaka et al. (1996) studied this question.
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