Why the study?
Do different volatile anesthetics (sevoflurane, isoflurane, halothane, enflurane) induce different hemodynamic and catecholamine responses during inhaled induction of anesthesia via mask in healthy adults?
Population
50 ASA physical status I patients, aged 20-40 yr, scheduled for elective minor surgery
Comparison
Inhalation of sevoflurane, isoflurane… vs Comparison among the four volatile anesthetics
Design
Other
Follow-up
15 minutes
Authors
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May influence volatile agent selection for mask induction; leaves open confirmation in randomized trials of higher-risk patients.
Do different volatile anesthetics (sevoflurane, isoflurane, halothane, enflurane) induce different hemodynamic and catecholamine responses during inhaled induction of anesthesia via mask in healthy adults?
Isoflurane and enflurane induce hyperdynamic cardiovascular responses during inhaled induction, whereas sevoflurane and halothane do not, suggesting a direct relationship between airway irritation and immediate cardiovascular changes.
Tanaka et al. (1996) studied this question.
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