Role of blood pressure in mediating the influence of salt intake on renin expression in the kidney

Wild-type (WT) mice and mice lacking angiotensin II type 1a receptors (AT(1a)-/-)

Low-salt diet (0.02%), unilateral renal artery stenosis, or administration of NOS inhibitor N-nitro-l-arginine methyl ester or adrenergic agonist phenylephrine

Normal or high salt intake

Number and distribution of renin-producing cells in the kidneysurrogate