Why the study?
What are the cardiac toxicities associated with 5-fluorouracil and capecitabine?
Population
Patients receiving 5-fluorouracil or capecitabine
Design
Case_series
Authors
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Expands recognized fluoropyrimidine cardiotoxicity spectrum beyond vasospasm; leaves open incidence, mechanisms, and management for prospective study.
What are the cardiac toxicities associated with 5-fluorouracil and capecitabine?
Clinicians should be aware that 5-fluorouracil and capecitabine can cause a wide spectrum of cardiotoxicities beyond vasospasm to avoid repeat toxicity.
Stewart et al. (2010) studied this question.
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