Why the study?
Although the QRS score is a known predictor of infarct size and adverse prognosis after STEMI, its relationship with the SYNTAX II score remained to be defined.
Does the Selvester QRS score predict the severity of coronary artery disease as measured by SYNTAX score II in patients with STEMI undergoing primary PCI?
Does the Selvester QRS score predict the severity of coronary artery disease as measured by SYNTAX score II in patients with STEMI undergoing primary PCI?
The Selvester QRS score is an independent predictor of the SYNTAX score II and can help assess the severity of coronary artery disease in patients with STEMI undergoing primary PCI.
QRS score correlates with SYNTAX II in STEMI; leaves open its added value for risk stratification in prospective cohorts.
Kontext: Je znĂĄmo, Ĺže skĂłre QRS je spolehlivĂ˝m prediktorem rozsahu infarktu a nepĹĂznivĂŠ prognĂłzy pacientĹŻ po infarktu myokardu s elevacemi Ăşseku ST (ST-segment elevation myocardial infarction, STEMI). CĂl: NaĹĄĂm cĂlem bylo definovat vztah mezi skĂłrovacĂmi systĂŠmy skĂłre SYNTAX II (SS-II) a skĂłre QRS u pa- cientĹŻ po STEMI. Metody: Do studie bylo zaĹazeno 302 po sobÄ nĂĄsledujĂcĂch pacientĹŻ (71,8 % muŞů, prĹŻmÄrnĂ˝ vÄk 55,1 ± 12,2 roku) po STEMI, lĂŠÄenĂ˝ch primĂĄrnĂ perkutĂĄnnĂ koronĂĄrnĂ intervencĂ (percutenous coronary intervention, PCI). Pacienti byli rozdÄleni do dvou skupin podle hodnot SS-II (jedinci s SS-II ≤ 32 tvoĹili skupinu s "nĂzkĂ˝m" skĂłre [n = 241], zatĂmco jedinci s SS-II > 32 pĹedstavovali skupinu se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" skĂłre [n = 61]). VĂ˝sledky: Pacienti se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" skĂłre byli starĹĄĂ. Hodnoty N-terminĂĄlnĂho fragmentu natriuretickĂŠho propeptidu typu B (NT-pro brain natriuretic peptide, NT-proBNP), troponinu, indexu skĂłre kinetiky srdeÄnĂ stÄny a perfuze myokardu mÄĹenĂĄ metodou TIMI frame count byly statisticky vĂ˝znamnÄ vyĹĄĹĄĂ ve skupinÄ se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" SS-II neĹž ve druhĂŠ skupinÄ (p < 0,05 pro vĹĄechny hodnoty). U pacientĹŻ ve skupinÄ se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" SS-II byla zjiĹĄtÄna nĂzkĂĄ ejekÄnĂ frakce (p < 0,001). Hodnoty souhrnnĂŠho sledovanĂŠho parametru byly statisticky vĂ˝znamnÄ vyĹĄĹĄĂ ve skupinÄ se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" SS-II (p = 0,01). Selvesterovo skĂłre QRS bylo statisticky vĂ˝znamnÄ vyĹĄĹĄĂ ve skupinÄ se "stĹednÄ vysokĂ˝m aĹž vysokĂ˝m" SS-II neĹž ve skupinÄ s "nĂzkĂ˝m" SS-II (p < 0,001). Bylo prokĂĄzĂĄno, Ĺže skĂłre QRS, hypertenze, kuĹĂĄctvĂ a hodnoty TIMI frame count pĹedstavujĂ nezĂĄvislĂŠ prediktory SS-II. MeznĂ hodnota skĂłre QRS predikujĂcĂ hodnotu SS-II na zĂĄkladÄ analĂ˝zy kĹivky ROC byla 9,0 pĹi senzitivitÄ 50,9 % a specificitÄ 84,1 % (AUC 0,726; 95% CI 0,648-0,804; p < 0,001). ZĂĄvÄr: SkĂłre QRS je spojeno se skĂłre SS-II predikujĂcĂm zĂĄvaĹžnost ischemickĂŠ choroby srdeÄnĂ a mortalitu pacientĹŻ se STEMI, u nichĹž byla provedena primĂĄrnĂ PCI. © 2021, ÄKS.
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Türkoğlu et al. (2021) studied this question.
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