Why the study?
The no-reflow phenomenon is a serious complication of PCI, and SYNTAX score II predicts mortality in ACS; this study aimed to determine the relationship between SYNTAX score II and the no-reflow phenomenon.
Is SYNTAX score II associated with the no-reflow phenomenon in patients with acute anterior STEMI undergoing primary PCI?
Cohort (n=255)
No
Is SYNTAX score II associated with the no-reflow phenomenon in patients with acute anterior STEMI undergoing primary PCI?
Effect estimate: OR 1.096 (95% CI 1.058-1.135)
p-value: p=<0.001
SYNTAX score II is an independent predictor of the no-reflow phenomenon in patients with anterior STEMI undergoing primary PCI.
SS-II may stratify no-reflow risk in anterior STEMI PCI; hypothesis-generating, needs prospective validation before practice change.
Kontext a cĂle: "No-reflow" fenomĂŠn spojenĂ˝ s ĂşmrtĂm na kardiovaskulĂĄrnĂ onemocnÄnĂ pĹedstavuje zĂĄvaĹžnou komplikaci perkutĂĄnnĂ koronĂĄrnĂ intervence. Pokud jsou znĂĄmy klinickĂŠ a angiografickĂŠ parametry pacienta, skĂłre SYNTAX II (SS-II) predikuje mortalitu pacientĹŻ s akutnĂm koronĂĄrnĂm syndromem (AKS). CĂlem tĂŠto studie je zjistit vztah mezi "no-reflow" fenomĂŠnem a SS-II. Pacienti a metody: Do studie bylo zaĹazeno 255 po osobÄ nĂĄsledujĂcĂch pacientĹŻ (210 [82,3 %] muŞů, prĹŻmÄrnĂ˝ vÄk 55 [18-90] let) s akutnĂm infarktem myokardu pĹednĂ stÄny s elevacemi Ăşseku ST (anterior ST-segment elevation myocardial infarction, STEMI), u nichĹž byla provedena primĂĄrnĂ perkutĂĄnnĂ koronĂĄrnĂ intervence. Pacienti byli rozdÄleni do dvou skupin; jednĂŠ s "no-reflow" fenomĂŠnem a druhĂŠ s obnovenĂ˝m prĹŻtokem krve ("reflow"). ZaznamenĂĄvaly se demografickĂŠ parametry, komorbidity i biochemickĂŠ parametry a byly vypoÄteny hodnoty skĂłre SYNTAX I (SS-I) i SS-II pacientĹŻ. VĂ˝sledky: Skupina "no-reflow" byla starĹĄĂ. Hypertenze byla pĹĂtomna ÄastÄji ve skupinÄ "no-reflow" neĹž ve skupinÄ s obnovenĂm prĹŻtoku krve (p = 0,007). U pacientĹŻ s "no-reflow" byly namÄĹeny vyĹĄĹĄĂ hodnoty troponinu (jak pĹi pĹĂjmu, tak maximĂĄlnĂ), TIMI frame count, hodnoty SS-I a SS-II byly statisticky vĂ˝znamnÄ vyĹĄĹĄĂ u pacientĹŻ s "no-reflow". V logistickĂŠ regresnĂ analĂ˝ze byla hodnota SS-II (pomÄr ĹĄancĂ [odds ratio, OR] 1,096; 95% interval spolehlivosti [confidence interval, CI] 1,058-1,135; p < 0,001) nezĂĄvisle spojena s "no-reflow" fenomĂŠnem. V analĂ˝ze kĹivky ROC predikovala meznĂ hodnota ≥ 24,85 pĹĂtomnost "no-reflow" fenomĂŠnu se senzitivitou 75,9 % a specificitou 59,2 % (AUC 0,721 [0,637-0,805], 95% CI; p < 0,001). ZĂĄvÄr: U pacientĹŻ se STEMI, zvlĂĄĹĄtÄ s akutnĂm infarktem myokardu pĹednĂ stÄny, je hodnota SS-II nezĂĄvisle spojena s "no-reflow" fenomĂŠnem jako fatĂĄlnĂ a Äastou komplikacĂ AKS. © 2021, ÄKS.
No takes yet. Share an insight, caveat, or question.
Harbalıoğlu et al. (2021) conducted a cohort in Acute anterior ST-segment elevation myocardial infarction (n=255). SYNTAX score-II was evaluated on No-reflow phenomenon (OR 1.096, 95% CI 1.058-1.135, p=<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: