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January 22, 2014Pediatric Diabetes

Meeting an increasing number of ICH metrics was significantly associated with lower arterial stiffness (lower PWV of the trunk β = -0.02 ±0.01, p = 0.004; AIx β = -2.2 ±0.66, p = 0.001; and increased BrachD β = 0.14 ±0.07, p = 0.04).

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Why the study?

Does meeting more ideal cardiovascular health metrics improve arterial stiffness in adolescents with type 1 diabetes?

Population

190 adolescents with type 1 diabetes from the SEARCH CVD study

Design

Cohort

Follow-up

average 5 years (interquartile range 4-5)

Authors

AAAmy C. AlmanUniversity of South FloridaJTJennifer W. TaltonDuke Medical CenterRWR. Paul WadwaThe Medical Center of Aurora

Discussion

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Member takes

Overview

Supports primordial prevention focus in type 1 diabetes adolescents; leaves open whether ICH interventions causally reduce stiffness or events.

Structured PICO

Does meeting more ideal cardiovascular health metrics improve arterial stiffness in adolescents with type 1 diabetes?

P
Population
190 adolescents with type 1 diabetes from the SEARCH CVD study
I
Intervention
Number of ideal cardiovascular health (ICH) metrics met at baseline
O
Outcome
Measures of arterial stiffness (pulse wave velocity [PWV], brachial distensibility [BrachD], and augmentation index [AIx]) and carotid intima-media thicknesssurrogate

In adolescents with type 1 diabetes, meeting more ideal cardiovascular health metrics is associated with decreased arterial stiffness, highlighting the need for primordial prevention in this high-risk group.

Cite This Study

Alman et al. (2014) studied this question.

synapsesocial.com/papers/6a73e9ac6acfb9d2a78ded66https://doi.org/10.1111/pedi.12120
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Also Consider

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  5. 5The epidemic of type 1 diabetes2011 · 117 citations