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August 8, 2014The Journal of Clinical Endocrinology & MetabolismOpen Access

Association of Serum C1q/TNF-Related Protein-9 Concentration With Arterial Stiffness in Subjects With Type 2 Diabetes

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Why the study?

Is serum CTRP9 concentration associated with arterial stiffness in subjects with type 2 diabetes?

Population

278 subjects with type 2 diabetes (169 men, 109 women; mean age 58.3 years)

Design

Cross-sectional

Authors

CJChang Hee JungMLMin Jung LeeYKYu Mi Kang

Discussion

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Overview

Serum CTRP9 may mark arterial stiffness in T2D; hypothesis-generating and requires prospective validation before any clinical role.

Structured PICO

Is serum CTRP9 concentration associated with arterial stiffness in subjects with type 2 diabetes?

P
Population
278 subjects with type 2 diabetes (169 men, 109 women; mean age 58.3 years)
O
Outcome
Arterial stiffness measured by brachial ankle pulse wave velocity (baPWV)surrogate

Elevated serum CTRP9 concentration is independently associated with increased arterial stiffness in patients with type 2 diabetes.

Cite This Study

Jung et al. (2014) studied this question.

synapsesocial.com/papers/6a73faaef2548bdd13cdec16https://doi.org/10.1210/jc.2014-2524
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Plasma C1q/TNF-Related Protein-9 Levels Are Associated with Atherosclerosis in Patients with Type 2 Diabetes without Renal Dysfunction2016 · 25 citations
  2. 2Association of circulating CTRP9 with soluble adhesion molecules and inflammatory markers in patients with type 2 diabetes mellitus and coronary artery disease2018 · 58 citations
  3. 3Association of serum CTRP9 levels with cardiac autonomic neuropathy in patients with type 2 diabetes mellitus2021 · 6 citations
  4. 4Associations of C1q/TNF-Related Protein-9 Levels in Serum and Epicardial Adipose Tissue with Coronary Atherosclerosis in Humans2015 · 53 citations
  5. 5Serum C1q/TNF-related protein-3 (CTRP3) levels are decreased in obesity and hypertension and are negatively correlated with parameters of insulin resistance2015 · 78 citations