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October 1, 1974Journal of Bone and Joint Surgery

Intramedullary Pressure and Pulmonary Embolism of Femoral Medullary Contents in Dogs during Insertion of Bone Cement and a Prosthesis

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Why the study?

Does drilling a distal hole prevent pulmonary embolization during insertion of bone cement and a prosthesis in dogs?

Population

8 greyhounds (dogs) undergoing insertion of bone cement and a medullary rod

Comparison

Drilling a hole distal to the cemented area… vs Insertion of cement and a medullary rod without…

Design

Preclinical

Follow-up

10 to 120 seconds

Authors

TKTamas KallosBaptist Hospital of MiamiJEJerry E. EnisMount Sinai Medical CenterFGFrank GollanMeharry Medical College

Discussion

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Implication

Distal venting may mitigate embolization risk in cementing; hypothesis-generating in canine model, human validation required.

Structured PICO

Does drilling a distal hole prevent pulmonary embolization during insertion of bone cement and a prosthesis in dogs?

P
Population
8 greyhounds (dogs) undergoing insertion of bone cement and a medullary rod
I
Intervention
Drilling a hole distal to the cemented area during insertion of cement and a medullary rod
C
Comparator
Insertion of cement and a medullary rod without a distal hole
O
Outcome
Femoral medullary pressures and pulmonary embolization of medullary contentssurrogate

Drilling a distal hole during bone cement insertion prevents high intramedullary pressure and subsequent pulmonary embolization in a canine model.

Cite This Study

Kallos et al. (1974) studied this question.

synapsesocial.com/papers/6a7441e8c2eb6969bf092e3fhttps://doi.org/10.2106/00004623-197456070-00004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1High-volume, high-pressure pulsatile lavage during cemented arthroplasty.1989 · 97 citations
  2. 2Hypotension during cemented arthroplasty. Relationship to cardiac output and fat embolism1993 · 88 citations
  3. 3Effect of Pressurized Cement Insertion on Cardiopulmonary Parameters during Cemented Hip Hemiarthroplasty: A Randomized Prospective Study2014 · 2 citations
  4. 4Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain2024 · 4 citations
  5. 5Cardiovascular Effects of Acrylic Bone Cement in Rabbits and Cats1973 · 30 citations