Why the study?
What factors contribute most to the risk of recurrent ischemic stroke?
What factors contribute most to the risk of recurrent ischemic stroke?
Cardiac conditions (MI, other heart diseases) and TIA are stronger predictors of recurrent ischemic stroke than traditional risk factors such as hypertension and diabetes.
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May prioritize cardiac history in post-stroke risk stratification; leaves open whether targeted interventions reduce recurrence.
We used the Lehigh Valley Stroke Register and a logistic regression model for the odds ratio to study the relative contribution of several factors, considered jointly, to the risk of recurrent ischemic stroke. The factors were hypertension (HT), transient ischemic attack (TIA), myocardial infarction (MI), other heart diseases (OHD), diabetes mellitus (DM), age, and sex. Among these factors MI, OHD, and TIA constituted significantly greater risk than HTN, DM, age, or sex for ischemic stroke recurrence.
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Sobel et al. (1989) studied this question.
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