Key result
Atrial fibrillation (OR 14.008), cerebral vascular stenosis (OR 5.819), and type 2 diabetes (OR 3.057) significantly increased the risk of recurrent mild ischemic stroke within 1 year.
Why the study?
Risk factors associated with recurrence in patients with mild ischemic stroke and the characteristics of high-risk groups needed to be examined.
Observational (n=656)
No
Odds Ratio: 14.008 (95% CI 7.246–27.081)
p-value: p=<0.001
In patients with mild ischemic stroke, older males with type 2 diabetes and hypertension are at high risk for recurrence at 1 year, with atrial fibrillation and cerebral vascular stenosis acting as major independent risk factors.
May aid recurrence risk stratification after mild ischemic stroke; leaves open whether targeting identified clusters improves outcomes.
ObjectiveThis observational study examined the risk factors associated with recurrence in patients with mild ischemic stroke and determined the characteristics of high-risk groups.MethodsA total of 656 patients hospitalized for mild ischemic stroke were monitored for 1 year. Statistical analyses, including odds ratio calculations and K-means clustering, were conducted to examine risk factors for recurrence and the characteristics of high-risk groups.ResultsAfter 1 year of follow-up, 99 patients experienced recurrent mild ischemic stroke, resulting in a recurrence rate of 15.09%. The analysis revealed several significant risk factors, including type 2 diabetes mellitus, atrial fibrillation, smoking and alcohol consumption, carotid artery stenosis, cerebral vascular stenosis, and multiple lesions. Propensity score matching confirmed these associations, and K-means clustering revealed that older males with type 2 diabetes mellitus and hypertension were likely to be in the high-risk group.ConclusionsHealthcare professionals should focus on tailored treatment and prevention strategies for high-risk patients, prioritizing the management of the abovementioned risk factors to reduce recurrence and improve outcomes.
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Huang et al. (2025) conducted an observational in Mild ischemic stroke (n=656). Atrial fibrillation vs. No atrial fibrillation was evaluated on Recurrent mild ischemic stroke within 1 year (OR 14.008, 95% CI 7.246-27.081, p=<0.001). Atrial fibrillation (OR 14.008), cerebral vascular stenosis (OR 5.819), and type 2 diabetes (OR 3.057) significantly increased the risk of recurrent mild ischemic stroke within 1 year.
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