Why the study?
Does using locked heparin as the loading dose maintain similar ACT and heparin levels compared to standard practice in hemodialysis patients?
Population
13 patients on hemodialysis with double-lumen dialysis catheters
Comparison
Catheter locked with the patient's predetermined… vs Standard practice: catheter locked with 10,000…
Design
Cohort
Follow-up
Four hemodialysis sessions
Authors
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Locked heparin loading yields comparable anticoagulation metrics; hypothesis-generating for reduced wastage, requiring RCTs before practice change.
Does using locked heparin as the loading dose maintain similar ACT and heparin levels compared to standard practice in hemodialysis patients?
Using locked heparin as the loading dose for hemodialysis catheters is effective, reduces blood wastage, and provides cost savings without compromising anticoagulation.
Trivedi et al. (1997) studied this question.
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