Key result
Reduced preprocedural TIMI flow grade (0-1) in STEMI patients was associated with greater lipid index (P=0.007) and larger plaque plus media cross-sectional area (P=0.030) than TIMI flow 2-3.
Observational (n=111)
In patients with STEMI, reduced preprocedural TIMI flow grade is associated with greater culprit plaque lipid burden, larger vessel sizes, and larger plaque areas on intracoronary imaging.
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May inform mechanisms of impaired flow in STEMI; leaves open need for prospective validation before clinical adoption.
Higuma et al. (2016) conducted an observational in ST-segment-elevation myocardial infarction (n=111). Reduced preprocedural TIMI flow grade (TIMI 0-1) vs. Preprocedural TIMI flow grade 2-3 was evaluated on Morphological characteristics of the culprit plaque. Reduced preprocedural TIMI flow grade (0-1) in STEMI patients was associated with greater lipid index (P=0.007) and larger plaque plus media cross-sectional area (P=0.030) than TIMI flow 2-3.
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