Key result
A resistive index of the ophthalmic artery >0.625 was identified as a cut-off value indicative of atherosclerotic disease in hypertensive patients.
Why the study?
Resistive index of ophthalmic artery (RI-OA) is associated with atherosclerotic diseases, but its association with hypertension-related vascular and kidney damage needed evaluation.
Is the resistive index of the ophthalmic artery associated with hypertension-related vascular and kidney damage in hypertensive patients?
Observational (n=280)
Is the resistive index of the ophthalmic artery associated with hypertension-related vascular and kidney damage in hypertensive patients?
The resistive index of the ophthalmic artery (RI-OA >0.625) may serve as a useful non-invasive imaging biomarker for identifying hypertension-related vascular and kidney damage.
Answers are grounded in this paper and cite their sources.
May support RI-OA for evaluating hypertensive organ damage; hypothesis-generating and requires prospective validation.
Aim: Resistive index of ophthalmic artery (RI-OA) is associated with atherosclerotic diseases. The aim of this study was to evaluate the association of RI-OA and hypertension-related vascular and kidney damage. Materials and methods: Two-hundred and eighty hypertensive patients underwent evaluation of RI-OA, carotid atherosclerosis and level of 24 h albuminuria. Results: Albuminuria and carotid atherosclerosis were positively associated with RI-OA independently of other cardiovascular risk factors. Receiver-operating characteristic curve analysis allowed us to calculate a cut-off value of RI-OA >0.625, which would be suspicious about the existence of atherosclerotic disease. Conclusion: The ophthalmic vascular circulation allows to study connections between macro- and microcirculation in vivo. RI-OA could be a useful marker for a better stratification of the risk of developing kidney and cardiovascular disease.
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Mattina et al. (2021) conducted an observational in Hypertension (n=280). Resistive index of ophthalmic artery (RI-OA) was evaluated on Albuminuria and carotid atherosclerosis. A resistive index of the ophthalmic artery >0.625 was identified as a cut-off value indicative of atherosclerotic disease in hypertensive patients.
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