Population
20 patients with idiopathic hypertriglyceridaemia with normal glucose tolerance, and 27 normal control…
Design
Case-control
Authors
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Distinguishes kinetic defects in Type IV vs V hypertriglyceridemia; hypothesis-generating for targeted therapies pending prospective validation.
Idiopathic hypertriglyceridemia is associated with enhanced lipolysis and secondary changes in insulin secretion and triglyceride transport, with differing primary kinetic abnormalities between Type IV and Type V phenotypes.
Adams et al. (1974) studied this question.
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